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Versatile dual wavelength X-ray diffractometer with HPC X-ray detector

A multi-functional single crystal X-ray diffractometer for a wide range of crystallographic applications

  • Access to two wavelengths in one compact system
  • 12x higher flux than sealed tube X-ray sources
  • Low maintenance, high performance system
  • Uses CrysAlisPro software with both PX and SMX modes
XtaLAB Synergy-DW
Small Molecule, Protein
Academic research, Chemistry, Pharmaceuticals
Single crystal X-ray diffraction, Chemical crystallography, Protein crystallography

XtaLAB Synergy-DW

One source with two high-flux wavelengths is the foundation of the revolutionary XtaLAB Synergy-DW single crystal X-ray diffractometer. It combines the increased flux of a rotating anode X-ray source with the flexibility of two different wavelengths, making it ideal for laboratories exploring a wide range of research interests.

Configuration

The XtaLAB Synergy-DW diffractometer is based on the proven, low-maintenance MicroMax-007 HF microfocus rotating anode. The target is constructed with two different X-ray source materials (Cu and Mo) and is coupled with an auto-switching dual wavelength optic. Copper or molybdenum X-ray radiation is available at the click of a button. The XtaLAB Synergy-DW offers up to 12x higher flux compared to the standard sealed tube X-ray sources and, utilizing only one generator, means overall maintenance is reduced. Rounding out the XtaLAB Synergy-DW configuration is the fast and efficient four-circle kappa goniometer which is compatible with a wide range of detectors including the HyPix-6000HE and other Hybrid Photon Counting (HPC) X-ray detectors e.g. PILATUS and EIGER detectors.

Benefits

  • Multi-functional diffractometer to cover you wherever your research takes you
  • High flux performance means you all your crystallography needs can be carried out ‘in-house’
  • Very little downtime and easy maintenance
  • No need to purchase extra software for different applications

Specifications

Product name XtaLAB Synergy-DW
Technique Single crystal X-ray diffraction
Benefit Fast structural analyses of a wide range of single crystals
Technology Dual wavelength X-ray diffractometer
Core attributes X-ray diffractometer with high-flux, dual wavelength X-ray source, kappa goniometer and HPC detector
Core options Oxford Cryostream cooler, XtalCheck-S
Computer External PC, MS Windows® OS, CrysAlisPro Software
Core dimensions 1300 (W) x 1875 (H) x 850 (D) (mm)
Mass 600 kg (core unit)
Power requirements 1Ø, 200-230 V, 20 A

Accessories

The following accessories are available for this product
ELement ANalyzer

The ELement ANalyzer is a state-of-the-art attachment that allows us to obtain qualitative information on elements in a single crystal at the same time as X-ray diffraction data collection for a single crystal structural analysis. By measuring the X-ray fluorescence spectrum emitted during X-ray diffraction experiments with the ELement ANalyzer, it becomes possible to perform elemental analysis on a single grain of crystal. The ELement ANalyzer can be used for confirmation the presence of central metal(s) in a mononuclear or polynuclear complex or solvent in a crystal for small molecule X-ray crystallography. There is a broad range of possible applications of the ELement ANalyzer in scientific fields.

ELement ANalyzer

ELement ANalyzerは単結晶試料の回折測定と元素分析(定性分析)を並行して行える画期的なアタッチメントです。回折測定中に試料から放出される蛍光X線をELement ANalyzerで計測することにより、結晶に含まれている元素を同定します。Mo線源の装置に組み合わせた場合、P(リン)より重い元素であれば、同定することができます*。RAPIDシリーズやSaturnシリーズなどの単結晶X線回折装置に組み合わせることができ、既存の装置を改造することなく取り付けが可能です。錯体の中心金属の有無や種類、結晶溶媒の有無を数分で確認できるため、無駄となる測定を減らし、研究を効率的に進めることができます。また、多核錯体の確認にも威力を発揮します。

Oxford Cobra

The Oxford Cobra is the non-liquid nitrogen Cryostream. Combining the efficiency of a Cryostream with the advantages of a non-liquid system, the Cobra offers the ultimate solution for both macromolecular and small molecule crystallography.

Oxford Cryostream 800

The 800 Series Cryostream is the most robust, efficient and user-friendly liquid nitrogen based low temperature system available today. Specific features include a superior laminar flow system, meaning virtually zero risk of icing, extremely quiet running and a fast-start system resulting in a cool-down time to 100K of just 20 minutes.

XtalCheck

The XtalCheck system includes software that facilitates both visual and diffraction imaging of crystallization experiments. With the XtalCheck system, one can easily survey many crystallization experiments by eliminating the need to harvest and cryo-cool samples. Moreover, one can perform serial crystallography experiments, by collecting data from multiple crystals, to achieve complete data sets that can be used for structure solution.

XtalCheck

手動タイプ PlateMate

  • シンプルかつ軽量で扱いやすいデザイン
    ゴニオメーターヘッドと同じマウント機構を採用。既存のX線回折装置に簡単に取り付けることができます。SBS規格に準拠した結晶化プレートに対応可能で、MiTeGen社製 In Situ–1 Crystallization Plateでの測定に適したデザインです。
  • 簡単かつ正確なセンタリング機構
    水平および垂直方向に搭載した目盛付きのレールに沿って結晶化プレートを動かすことで、すべてのウェルに対して簡単にセンタリングすることができます。また、微調整機構により、微小な結晶であっても正確なセンタリングが可能です。
  • 結晶化プレート中の結晶を測定
    見分けのつきにくいタンパク質結晶と塩・沈殿剤などの結晶を、ドロップ内から取り出すことなく迅速に判別し、さらに分解能などの品質をチェックできます。
  • 構造解析用のデータ収集も可能
    スクリーニング目的のX線回折像取得のみならず、構造解析用の回折強度データの収集も可能です。結晶化溶媒から取り出すだけで損傷してしまうような特殊な結晶も、その環境下で測定できます。

電動タイプ XtalCheck

  • GUIからコントロール
    すべての機能はGUIから操作できます。
    モーター制御により、微小な結晶であっても正確なセンタリングが可能です。また、複数のウェルや、ドロップ内の複数の結晶を事前に指定することで、簡単な操作で複数の結晶を一度に評価できます。